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Drug Detection Time in Urine

Drug/Identifier Cut-off Level† Minimum Maximum
Marijuana (THC) 50 ng/ml 2 hours Up to 40+ days
Cocaine (COC) 300 ng/ml 1-4 hours 2-4 days
Methamphetamine (MET) 1000 ng/ml 2-7 hours 2-4 days
Amphetamines (AMP) 1000 ng/ml 2-7 hours 2-4 days
Ecstasy (MDMA) 500 ng/ml 2-7 hours 2-4 days
Opiates (heroin) (OPI) 2000 ng/ml 2 hours 2-3 days
Phencyclidine (PCP) 25 ng/ml 4-6 hours 7-14 days
Benzodiazepines (BZO)* 300 ng/ml 2-7 hours 1-4 days
Methadone (MTD) 300 ng/ml 3-8 hours 1-3 days
Barbiturates (BAR) 300 ng/ml 2-4 hours 1-3 weeks
Tricyclic Antidepressants (TCA) 1000 ng/ml 8-12 hours 2-7 days
Oxycodone (OXY) 100 ng/ml 1-3 hours 1-2 days


*Benzodiazepines are detected dependent on whether they are long-acting (up to 10 days), intermediate-acting (up to 5 days) or short-acting (up to 2 days).  In addition, other factors such as dose taken, route of administration, time of last dose and individual differences in pharmacokinetics will impact detection of the benzodiazepine.

† The Substance Abuse and Mental Health Services Agency (SAMHSA), has set “cut-off” levels when testing for marijuana, cocaine, methamphetamine, amphetamines, ecstasy, opiates, and PCP. First Check is manufactured to conform to those standards. Screening tests may not detect amounts of drugs in a urine sample that are below the cut-off level. Even though some level of drug may be present in a urine sample, the sample would still be considered Negative Result if the drug level is below the cut-off level.