Detection Cut-Off Levels

Drug Detection Time in Urine

Drug/IdentifierCut-off Level†MinimumMaximum
Marijuana (THC) 50 ng/ml 1-4 hours 7 days
Cocaine (COC) 300 ng/ml 1-4 hours 2-4 days
Methamphetamine (MET) 1000 ng/ml 2-7 hours 2-4 days
Amphetamines (AMP) 1000 ng/ml 2-7 hours 2-4 days
Ecstasy (MDMA) 500 ng/ml 2-7 hours 2-4 days
Opiates (heroin) (OPI) 2000 ng/ml 2 hours 2-3 days
Phencyclidine (PCP) 25 ng/ml 4-6 hours 7-14 days
Benzodiazepines (BZO)* 300 ng/ml 2-7 hours 1-4 days
Methadone (MTD) 300 ng/ml 3-8 hours 1-3 days
Barbiturates (BAR) 300 ng/ml 2-4 hours 1-3 weeks
Tricyclic Antidepressants (TCA) 1000 ng/ml 8-12 hours 2-7 days
Oxycodone (OXY) 100 ng/ml 1-3 hours 1-2 days


*Benzodiazepines are detected dependent on whether they are long-acting (up to 10 days), intermediate-acting (up to 5 days) or short-acting (up to 2 days). In addition, other factors such as dose taken, route of administration, time of last dose and individual differences in pharmacokinetics will impact detection of the benzodiazepine.


† First Check® Home Drug Tests use specific “cut-off” levels. Screening tests may not detect amounts of drugs in a sample that are below the cut-off level. Even though some level of drug may be present in a sample, the sample would still be considered a Negative Result if the drug level is below the cut-off level.

Before taking the test, users must read all of the content in the package insert. For a list of reactive and non-reactive drugs, see the drug testing guides, which can be found on the Instructions tab within the product pages.

Patented Lid Technology

First Check's home drug test kits use patented, tamper-free lid technology for visible, accurate results in minutes.